ODCs

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Familial gastric cancer

1 OMIM reference -
2 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 2

Muir-Torre syndrome

1 OMIM reference -
3 associated genes
14 signs/symptoms

Familial gastric cancer

Muir-Torre syndrome

CDH1	(UniProt - OMIM)		MLH1	(UniProt - OMIM)
MUTYH	(UniProt - OMIM)		MSH2	(UniProt - OMIM)
			MSH6	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MUTYH MUTYH	(0.71) (0.68)	MSH6 MSH2

Citations in the biomedical literature:

Familial gastric cancer		Muir-Torre syndrome
	Synonym(s): - Familial stomach cancer		Synonym(s): - Multiple keratoacanthoma, Muir-Torre type

	Classification (Orphanet): - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease		Classification (Orphanet): - Rare eye disease - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease - Rare skin disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: - Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D055653

Muir-Torre syndrome
	Very frequent - Adenoma sebaceum - Autosomal dominant inheritance - Skin tumors / lumps / epidermal cysts Frequent - Colon neoplasm / tumor / carcinoma / cancer - Estomach / gastric neoplasm / tumor / carcinoma / cancer Occasional - Breast neoplasm / tumor / carcinoma / cancer - Hematologic / blood / lymphatic cancer - Hepatic / liver neoplasm / tumor / carcinoma / cancer - Kidney / renal neoplasm / tumor / carcinoma / cancer - Laryngeal neoplasm / tumor / carcinoma / cancer - Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) - Salivary gland neoplasm / tumor / carcinoma / cancer - Ureteral / urethral / vesical / bladder neoplasm / tumor / carcinoma / cancer - Uterus / uterine / cervix / endometrium neoplasm / tumor / carcinoma / cancer
Familial gastric cancer
(no data available)